Scarface gets the idea to have Thurgood steal medical marijuana from his work so that the three of them can sell it to raise money to free Kenny. His friends are forced to raise $1 million to bail him out before the other prisoners take advantage of his gentle nature. When Kenny, a gentle kindergarten teacher, is out on a munchie run, he is arrested for accidentally killing a diabetic police horse by feeding it junk food.

Thurgood, a janitor at a medical laboratory, brings home some unusually potent marijuana given to him by a scientist at the lab, and the four smoke it.

Four lifelong stoners and friends (Kenny, Thurgood, Scarface, and Brian) live together in New York City.